Organofluorine Chemistry
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Congratulations to Qinghe Liu, on having published an Angew. Chem. paper!
Date:2016/11/24

Stereoselective Carbonyl Olefination with Fluorosulfoximines: Facile Access to Z or E Terminal Monofluoroalkenes 
Liu, Qinghe; Shen, Xiao; Ni, Chuanfa; Hu, Jinbo*
Angew. Chem., Int. Ed. 2017, 56, 619 - 623.
 

Abstract:

       Showing Off New Skills: Fluorinated sulfoximines, known as fluoroalkylation reagents for the asymmetric synthesis of organofluorine compounds, have now been found to act as carbonyl-olefination reagents. This newly discovered reactivity was used to tackle the long-standing challenge of the stereoselective synthesis of terminal monofluoroalkenes from the corresponding aldehydes or ketones (see scheme).






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